Solitary fibrous tumor of pleura

Case contributed by Jeremy Jones
Diagnosis certain
x-ray

Large left basal pleural mass adjacent to the diaphragmatic surface.

CT confirms the large pleural mass at the left diaphragm with internal calcification.

Clinical Details:

Probable fibroma. Cacification on CT. Large left basal mass

Macroscopic Description:

Three cores, the largest 5x1x1mm.

Microscopic Description:

One of these cores consists of vascular collagenous tissue in which there is a dispersed population of cytologically bland spindle-shaped cells that are immunopositive for CD34 and bcl2 but immunonegative for AE1/3, MNF116, CD31, calretinin, SI00, SMA, desmin and caldesmon.

These appearances are those of a solitary fibrous tumor (also known as submesothelial fibroma).

DIAGNOSIS:

Solitary fibrous tumor

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