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What is the cause of the T1 bright signal in posterior pituitary lobe?
High concentration of vasopressin results in the posterior pituitary bright spot.
This contrast enhanced dynamic MR shows an absent posterior pituitary bright spot on the pre-enhanced T1WI.
The MR also shows a thick (3.8 mm, normal is < 2.4 mm), but normally enhancing pituitary stalk.
In absence of any other biochemical finding or significant clinical history, one would consider autoimmune disorder as the likely cause.