Diffuse pulmonary neuroendocrine cell hyperplasia with probable carcinoid

Discussion:

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare disorder and information on this disease is limited, especially with regard to its management and prognosis. It has become generally accepted that DIPNECH is a precursor lesion to pulmonary carcinoid tumors.

The majority of patients are middle-aged women who present with symptoms of cough and dyspnea, obstructive abnormalities on pulmonary function testing and pulmonary nodules, and bronchiectasis.

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