There is prominent diffusion restriction of essentially the whole left caudate nucleus. Suspected subtle diffusion restriction along the right caudate and bilateral thalami, the latter particularly in the region of the left pulvinar. Associated increased T2 signal of the left caudate nucleus, as well as in the putamina and to a lesser extent thalami. No mass-effect.
Sulci are borderline prominent for age. No selective brainstem or cerebellar atrophy. At least one small old infarct noted in the right cerebellar hemisphere. Several small punctate foci of FLAIR hyperintensity in the supratentorial white matter most probably represents mild small vessel ischaemia.
Mild mineralisation of the globus pallidi. Paranasal sinus mucosal disease, left greater than right.
Conclusion
Although asymmetric, findings are most suspicious for CJD