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Rhabdoid meningioma

Case contributed by Azza Elgendy
Diagnosis almost certain

Presentation

Headache.

Patient Data

Age: 20 years
Gender: Female

Note: This case has been tagged as "legacy" as it no longer meets image preparation and/or other case publication guidelines.

ct

Axial NECT shows mixed solid (hyperdense) and cystic right frontal intra-axial mass with extensive vasogenic edema and mass effect. The solid areas of the mass are dense.

mri

Large mixed solid and cystic mass arising in the right frontal lobe and extending into subcallosal region causing an upward displacement of the genu of corpus callosum. The solid component is isointense in relation to the grey matter. There is mass effect on anterior horns of lateral ventricle and 10 mm leftward shift. 

There is moderate peritumoral edema that extends into the insular subcortical white matter. The anterior commissure deviated posteriorly due to the mass effect.

GRE hypointensities are suggestive of calcifications or blood products. There are DWI hyperintense signals suggestive of hypercellularity.

There is homogeneous enhancement of the solid component of the tumor and marginal enhancement surrounding the cystic components as well.

Case Discussion

The patient had a resection and the biopsy demonstrated a malignant meningioma with rhabdoid features, likely meningeal in origin (WHO grade III).

Meningioma with rhabdoid morphology is associated with a poor prognosis, regardless of tumor histogenesis.

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