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Are pancreatic neuroendocrine tumours more frequently isolated lesions or part of systemic syndromes? Can you name some important syndromes associated with these tumours?
Most tumours are isolated. 1-2% are associated with the multiple endocrine neoplasia type I (MEN I - characterised by the triad of parathyroid, pituitary, and pancreatic lesions). There are also associations between pancreatic endocrine tumours and von Hippel-Lindau and tuberous sclerosis.
Pancreatic head mass lesion, well defined with no vascular invasion noted.
No enlarged lymph nodes are visualised.
Biopsy was performed, there were no complications.