Presentation
Headache and disturbed conscious level.
Patient Data
Large left temproparietal paramedian intra-axial space occupying lesion that is resting medially on the falx cerebri and involves the left forceps major fibers as well as the splenium of the corpus callosum. The lesion displays low T1, bright T2/FLAIR signal with extensive central necrosis and peripheral marginal and nodular enhancement. There are central areas of mild diffusion restriction and susceptibility artifacts. It is surrounded by moderate perifocal edema and exerts positive mass effect in form of anterior displacement of the occipital horn of ipsilateral lateral ventricle and 1 cm rightward midline shift.
Case Discussion
The imaging findings are characteristic of a glioblastoma.
The patient underwent surgery and the diagnosis was confirmed histologically.
Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumors, this tumor would, therefore, be designated as a glioblastoma NOS.
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