Hemangioblastoma: von Hippel-Lindau syndrome

Discussion:

Final Diagnosis:

Cerebellum: Hemangioblastoma (clinical history of von Hippel-Lindau syndrome).

Microscopic Description:

Sections show the specimen to consist of a vascular tumor associated with small portions of cerebellar tissue. The tumor is characterized by a capillary component, large ectatic vascular structures and cystic elements containing proteinaceous fluid. These structures are within a stromal tumor background composed of clear cells with small round nuclei. In areas, focal permeation into cerebellar tissue is observed.

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