What condition should be considered as a likely diagnosis?
Familial multiple cavernous malformation syndrome. The patient should be offered counselling and genetic testing if possible. Screening of the family members by MRI is recommended.
Multiple nodular foci of low signal and marked blooming artefact are again demonstrated scattered through the brain, brainstem, and cerebellum, with at least two new foci when compared to the last MRI brain. Bilateral subcortical low signal consistent with haemosiderin staining are again demonstrated, more significant in the right frontoparietal region. No evidence of acute haemorrhage. Ventricles and basal cisterns are normal in appearance. MRA demonstrates no malformation, aneurysm, stenosis or other vascular abnormality.