Abnormal bilateral periventricular white matter hyperintensity in the frontal lobes on the fluid-sensitive sequences. The frontal lobes show a bizarre pattern of shallow sulci oriented parallel to each other with slightly thickened cortices and bumpy grey-white matter interfaces - pachygyria.
There is bilateral temporoparietal polymicrogyria.
The corpus callosum has a bizarre configuration, though not hypoplastic. There is marked pontine and inferior vermian hypoplasia and collicular fusion. The pontine hypoplasia leads to a Z configuration.
Disorganised cerebellar folia with multiple subcentimeter cysts are seen in the posterior and inferior cerebellar hemispheres.
In view of the characteristic distribution of cortical dysplasia, cerebellar abnormalities and relatively preserved general configuration of the brain, a probable diagnosis of Fukuyama congenital muscular dystrophy is considered.