Rib chondroma / low grade chondrosarcoma

Discussion:

Enchondromas (or chondromas ) are a relatively common benign medullary cartilaginous neoplasm with benign imaging features. Mostly, they are an incidental finding. They are usually asymptomatic. It is important to note that if an enchondroma is painful in the absence of a fracture, it should be considered malignant.

Distinguishing between enchondromas and low-grade conventional chondrosarcomas is a frequent difficulty as the lesions are both histologically and radiographically very similar. It is important to remember, though, that differentiating between them may be a moot point since both can either be closely followed up clinically and radiologically or treated if symptomatic. The large size and pain favor chondrosarcomas.

Another differential diagnosis could be added which is fibrous dysplasia due to the variability of the appearance of fibrous dysplasia. 

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