H&E and Ziehl-Neelsen stains
Histopathology: The sections show a cerebral abscess. The contents comprise necrotic inflammatory debris. This is delimited by a layer of inflamed vascular granulation tissue. There is an encompassing mantle of oedematous and gliotic brain parenchyma in which there are multiple foci of active cerebritis. There is no evidence of tumour. Numerous acid-fast bacilli with beaded morphology are identified in a Ziehl-Neelsen stained section.
DIAGNOSIS: Tuberculous cerebral abscess.
