Which routine cranial findings that you are expected to image on first trimester US are not featured here ? What is the most likely diagnosis ? Could this finding be part of a syndromic condition ?
No cerebral flax, hence no cleavage of lateral ventricles and choroid plexus. Holoprosencephaly, alobar form. Trisomy 13.
Normal skull shape, normal posterior fossa and cerebellum for 15 weeks of pregnancy.
No midline falx, fused thalami, single ventricle with a single choroid plexus.
3D examination of the face is consistent with unfused maxillary buds (facial cleft).