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Glioblastoma NOS

Case contributed by Rodrigo Dias Duarte
Diagnosis almost certain

Presentation

History of a progressive headache. Diagnosis confirmed by biopsy. Patient in follow-up, with previous radiotherapy.

Patient Data

Age: 70 years
Gender: Female

MRI Brain

mri

MRI demonstrates an intra-axial mass involving the right temporal lobe, predominantly hypointense on T1 and hyperintense on T2, exhibiting a heterogeneous and peripheral enhancement in the post-contrast study.
Midline shift, cerebral edema and marked mass effect, especially upon the atrium, are noted.
Also is seen hyperintense areas involving supratentorial white matter on T2 and FLAIR weighted imaging, probably secondary to microangiopathy and/or radiotherapy.

 

Case Discussion

The patient has had the diagnosis confirmed by biopsy and histology demonstrated a glioblastoma but with unavailable IDH mutation status, then this tumor has been classified as a glioblastoma NOS.

 

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