Ampullary tumor

Discussion:

There are two tumors that arise from the glandular epithelium of the ampulla of Vater: benign (adenoma) and malignant (adenocarcinoma).

When the tumor is small in size and limited to the ampulla, the endoscopic as well as the radiological appearances may be normal. But if the tumor is larger it can be visible on endoscopy as a prominent papilla or mural mass, and as a soft tissue mass protruding into the 2nd portion of the duodenum with a “double duct sign” on CT or MRI.

The sensitivity and specificity of endoscopic ultrasound in performing preoperative tumor and node staging are superior to those of MRI or CT.

The prognosis is even better for patients with a limited stage of disease.

Additional Contributor: Z.Boudiaf, MD.

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