Nuclear medicine - PET-CT (18F-FDG)
There are numerous FDG avid enlarged lymph nodes above and below the diaphragm, splenomegaly and numerous lung nodules consistent with high-grade lymphoma.
Above the diaphragm, metabolically active nodes are evident in Waldyers ring, bilateral cervical chain, left axillary and subpectoral, extensively throughout the mediastinum and right internal mammary stations.
Below the diaphragm, disease is present in the left crural, portahepatic, portacaval, coeliac axis, mesenteric root, para-aortic, bilateral iliac chains and right inguinal nodes.
The spleen is enlarged and intensely metabolically active in keeping with splenic involvement.
The extensive extranodal disease is present throughout the lungs bilaterally.
Osseous deposits are present in the left sacrum, left iliac bone, L1 spinous process, and T2 and L3 vertebral bodies.
Patchy marrow uptake is noted but non-specific. It does not have the same metabolic signature as the nodal and solid organ disease possible reflecting separate marrow infiltrative process, likely AML in this case.
Normal uptake in the testes. Physiological uptake is present elsewhere.