Metastatic neuroblastoma

Discussion:

Craniocerebral neuroblastoma metastases usually involve the calvaria, orbits, skull base and the dura.

Radiographic features:

CT:

  • spiculated periorbital bone mass, typically involving the roof or lateral wall/sphenoid wings
  • "hair on end" spiculated periostitis of orbits and skull usually associated with bone destruction
  • sutural separation: non-uniform sutural separation with indistinct sutures margins
  • cranial metastasis nearly always extradural (may mimic epidural or subdural hematoma)
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