Macroscopy: Labelled "Gall bladder". Disrupted gallbladder measuring 97 x 37 mm. Wall thickness is up to 10 mm. Mucosa is grey/brown with roughened texture. 3 yellow pigmented gallstones, the largest 17 mm. No lesions are identified. Cystic duct node is not identified.

Microscopy: The sections of the gallbladder wall show broad areas of ulceration, the residual epithelium shows reactive changes. There is an associated dense transmural active chronic inflammatory cell infiltrate extending into the adventitia where there are a prominent reactive fibroblastic response and abscess formation. The included mesothelium shows areas of fibrinous serositis and reactive changes. The cystic duct node shows reactive features. There is no evidence of malignancy. 

Conclusion: Gallbladder: Acute cholecystitis and cholelithiasis. 

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