Primary synovial osteochondromatosis

Case contributed by Ahmed D. Abdulwahab , 18 Jun 2020
Diagnosis certain
Changed by Mostafa Elfeky, 19 Jun 2020

Updates to Case Attributes

Presentation was changed:
36 yrs old male patient presented with painPain and limitation of movement of the right elbow joint for 2 years
Age changed from 36 yrs. to 35 years.
Body was changed:

Synovial osteochondromatosis is a benign condition of idiopathic causes, usually it is mono articularmonoarticular and predominantly in males in their 3rd to 5th decade.

In this condition, there is a proliferation and metaplastic transformation of the synovium resulting in formation of multiple cartilaginous nodules. Clinically it present with joint pain, swelling, and limitation of motion.

At the beginning the active phase showshows synovial proliferation and formation of intrasynovial cartilaginous nodules and progress to the final phase in which inactive synovial disease and nodules are present, these nodules may break off into the joint space. These nodules may contain only cartilage (synovial chondromatosis), cartilage and bone (osteochondomatosis), or mature bone with fatty marrow. they derive their nutrition from the synovial fluid. 

When calcified bodies are present, the radiographic findings consistsconsist of multiple intra articular-articular calcified nodules of uniform in size may be associated with a mild joint effusion, marginal erosion, and late secondary degenerative joint disease.

On MRI the appearances are variable, non mineralized-mineralized lesions are formed of cartilage and give cartilage signal intensity (that is isointense relative to muscle on T1-weighted images and hyperintense on T2-weighted images ).when. When the nodules contain calcification, small areas of low signal intensity are observed with all pulse sequences. when mature bone forms and fatty marrow display low signal intensity of cortical bone peripherally and high signal intensity of bone marrow fat centrally on T1-weighted images.

One thing to note when diagnosing primary synovial osteochondromatosis is that the joint itself is essentially normal at the beginning, degenerative changes only happen at the late stages. 

  • -<p>Synovial osteochondromatosis is a benign condition of idiopathic causes, usually it is mono articular and predominantly in males in their 3rd to 5th decade</p><p>In this condition there is a proliferation and metaplastic transformation of the synovium resulting in formation of multiple cartilaginous nodules. Clinically it present with joint pain, swelling, and limitation of motion .</p><p>At the beginning the active phase show synovial proliferation and formation of intrasynovial cartilaginous nodules and progress to the final phase in which inactive synovial disease and nodules are present, these nodules may break off into the joint space. These nodules may contain only cartilage (synovial chondromatosis), cartilage and bone (osteochondomatosis), or mature bone with fatty marrow. they derive their nutrition from the synovial fluid. </p><p>When calcified bodies are present, the radiographic findings consists of multiple intra articular calcified nodules of uniform in size may be associated with a mild joint effusion, marginal erosion, and late secondary degenerative joint disease.</p><p>On MRI the appearances are variable, non mineralized lesions are formed of cartilage and give cartilage signal intensity (that is isointense relative to muscle on T1-weighted images and hyperintense on T2-weighted images ).when the nodules contain calcification, small areas of low signal intensity are observed with all pulse sequences. when mature bone forms and fatty marrow display low signal intensity of cortical bone peripherally and high signal intensity of bone marrow fat centrally on T1-weighted images .</p><p>One thing to note when diagnosing primary synovial osteochondromatosis is that the joint itself is essentially normal at the beginning, degenerative changes only happen at the late stages. </p>
  • +<p>Synovial osteochondromatosis is a benign condition of idiopathic causes, usually it is monoarticular and predominantly in males in their 3rd to 5th decade.</p><p>In this condition, there is a proliferation and metaplastic transformation of the synovium resulting in formation of multiple cartilaginous nodules. Clinically it present with joint pain, swelling, and limitation of motion.</p><p>At the beginning the active phase shows synovial proliferation and formation of intrasynovial cartilaginous nodules and progress to the final phase in which inactive synovial disease and nodules are present, these nodules may break off into the joint space. These nodules may contain only cartilage (synovial chondromatosis), cartilage and bone (osteochondomatosis), or mature bone with fatty marrow. they derive their nutrition from the synovial fluid. </p><p>When calcified bodies are present, the radiographic findings consist of multiple intra-articular calcified nodules of uniform in size may be associated with a mild joint effusion, marginal erosion, and late secondary degenerative joint disease.</p><p>On MRI the appearances are variable, non-mineralized lesions are formed of cartilage and give cartilage signal intensity (that is isointense relative to muscle on T1-weighted images and hyperintense on T2-weighted images ). When the nodules contain calcification, small areas of low signal intensity are observed with all pulse sequences. when mature bone forms and fatty marrow display low signal intensity of cortical bone peripherally and high signal intensity of bone marrow fat centrally on T1-weighted images.</p><p>One thing to note when diagnosing primary synovial osteochondromatosis is that the joint itself is essentially normal at the beginning, degenerative changes only happen at the late stages. </p>

References changed:

  • 1. Sheldon J. Patrick et. al., Imaging of intra-articular masses, Radiographics, 2005, Vol. 25 No.1, RSNA
  • Sheldon J. Patrick et. al., Imaging of intra-articular masses, Radiographics, 2005, Vol. 25 No.1, RSNA

Updates to Study Attributes

Caption was added:
Right elbow joint
Findings was changed:

X-ray of the right elbow showing frontal and lateral views showing multiple intra articular-articular faintly calcified loose bodies (mainly seen anterior to the humeral supracondylar region), the elbow joint space appears intact. findingsFindings are indicative of synovial osteochondromatosis. 

Updates to Study Attributes

Caption was added:
Right elbow joint
Findings was changed:

right elbow joint MRI showing mildMild to moderate joint effusion with multiple intra-articular loose bodies seen within the synovial capsule both anterior and posterior to the joint, these loose bodies ragesrange from 3 to 5 mm in diameter each, they appear hypointense on T1 weighted images, hypointense on T2 weighted images (indicating calcified loose bodies), the. The elbow joint itself appears essnetiallyessentially normal, no signs of erosion, no joint destructive changes, no osteoarithriticosteoarthritic changes seen.  

Updates to Quizquestion Attributes

Answer was changed:
multipleMultiple faintly calcified loose bodies seen anterior to the elbow joint (the anterior supracondylar aspect of the humerus).

Updates to Quizquestion Attributes

Answer was changed:
Mild to moderate joint effusion multiple intra-articular loose bodies seen within the synovial capsule both anterior and posterior to the joint, hypointense on T1 weighted images, hypointense on T2 weighted images (indicating calcified loose bodies), the elbow joint itself appears essnetiallyessentially normal.

Updates to Quizquestion Attributes

Answer was changed:
Primary synovial osteochondromatosis Secondary and secondary synovial osteochondromatosis

Updates to Quizquestion Attributes

Answer was changed:
In the primary form, the patient is younger (3rd to 5th decade), no definite cause and the joint is normal. In the secondary form the patient is older with degenerative joint disease.

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