Differential diagnosis of bilateral basal ganglionic calcification
Long list of differential diagnosis: • Idiopathic: Fahr disease •Metablic (calcium disorders ) Parathyroid disorders 1. Hypoparathyroidism 2. Pseudo-hypoparathyroidism 3. Pseudopseudohypoparathyroidism 4. Hyperparathyroidism 5.Hypothyroidism Other less possibilities couldn't be totally excluded as: • Toxic 1. Carbon monoxide poisoning 2. Lead poisoning 3. Mineralizing microangiopathy • Inherited 1. Mitochondrial diseases e.g. MELAS 2. Pantothenate kinase-associated neurodegeneration (PKAN) (also known as Hallervorden-Spatz syndrome) 3. Birth hypoxia • Infectious 1. TORCH 2. Neurocysticercosis
Multiple bilateral symmetrical dense calcification within the basal ganglia, thalami and cerebellum as well as subcortical frontal, parietal and to lesser extent temporal and occipital lobes