Pathology
H&E
H&E
H&E
H&E
H&E
H&E
H&E
H&E
H&E
H&E
H&E
Sections show brain tissue containing a well-circumscribed tumour. The tumour is composed of a hypocellular amorphous-to-fibrillar core. Peripheral "ropey" cords are present. Some osteoid is identified within the tumour. There is a peripheral rind of spindled-to-epithelioid cells at the interface of the tumour with the surrounding brain.
The surrounding brain is gliotic and contains haemosiderin laden macrophages. There is no evidence of malignancy.
FINAL DIAGNOSIS: calcifying pseudoneoplasm of the neuroaxis (CAPNON).
Pathology slides and captions courtesy of Dr Samuel Roberts-Thomson, neuropathologist, Royal Melbourne Hospital.