Histological report bone biopsy (translation from italian to english)
Presence of multinuclear giant osteoclasts. Increase of osteoclasts and resorption cavities, active osteoblasts, increase of osteoid and widening of osteoid seam, mosaic structure of the bone trabeculae and bone marrow fibrosis. Osteoblasts extremely active, tall and densely distributed, occasionally in multiple layers. The nuclei eccentrically located with occasional atypia.