Adenocarcinoma lung, hypertrophic osteoarthropathy

Case contributed by Liz Silverstone , 3 Sep 2021
Diagnosis certain
Changed by Henry Knipe, 16 Sep 2021

Updates to Study Attributes

Findings was changed:

Right middle lobe bronchus occluded by a mass. Distal drowned airways, collapse &and consolidation. Within the collapsed middle lobe is a necrotic mass causing the fissures to bulge.

Right hilar and mediastinal lymphadenopathy.

Expanded lytic left rib lesion.

Right adrenal mass.

Updates to Case Attributes

Body was changed:

Primary adenocarcinoma was diagnosed by lung biopsy, - stage IVb due to multiple extra-thoracic metastases (bone and adrenal). The left knee pain was caused by metastatic destruction of the subarticular medial femoral condyle.

Layered periosteal new bone is typical of hypertrophic osteoarthropathy, a recognised paraneoplastic effect of lung cancer. 

Omission errors and satisfaction of search: Initially it was assumed that the pain was due to HOA or inflammation in the knee joint. The metastasis was missed due to failure of perception (omission error) and the presence of multiple abnormalities (satisfaction of search).

  • -<p>Primary adenocarcinoma was diagnosed by lung biopsy, - stage IVb due to multiple extra-thoracic metastases (bone and adrenal). The left knee pain was caused by metastatic destruction of the subarticular medial femoral condyle.</p><p>Layered periosteal new bone is typical of hypertrophic osteoarthropathy, a recognised paraneoplastic effect of lung cancer. </p><p>Omission errors and satisfaction of search: Initially it was assumed that the pain was due to HOA or inflammation in the knee joint. The metastasis was missed due to failure of perception (omission error) and the presence of multiple abnormalities (satisfaction of search).</p>
  • +<p>Primary adenocarcinoma was diagnosed by lung biopsy - stage IVb due to multiple extra-thoracic metastases (bone and adrenal). The left knee pain was caused by metastatic destruction of the subarticular medial femoral condyle.</p><p>Layered periosteal new bone is typical of hypertrophic osteoarthropathy, a recognised paraneoplastic effect of lung cancer. </p><p>Omission errors and satisfaction of search: Initially it was assumed that the pain was due to HOA or inflammation in the knee joint. The metastasis was missed due to failure of perception (omission error) and the presence of multiple abnormalities (satisfaction of search).</p>

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