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There is moderate reduction in uptake in bilateral parietal lobes, especially the precuneus and lateral parietal cortex. Mild-moderate reduction of uptake in the occipital lobes and mild reduction in the superior frontal cortex. Normal uptake is present in the posterior cingulate gyrus.
A "cingulate island sign" (arrow) is produced when the posterior cingulate gyrus has normal metabolism and there is abnormal reduced uptake in the adjacent parietal and occipital lobes. This gives the appearance of a discrete 'island' of comparatively more intense uptake in the region of the posterior cingulate gyrus.