The susceptibility-weighted sequence shows innumerable hypointense lesions (greater than 100 in number) throughout the gray and white matter of the cerebral hemispheres, the basal ganglia, thalami, brainstem and cerebellum. They demonstrate blooming artifact and are consistent with cavernomas with hemosiderin staining. They are much more numerous than appreciated on the CT.
The largest lesion represents the previously noted partially calcified right cerebellar lesion. This lesion measures 2.5 x 2.3 x 1.4 cm. No adjacent vasogenic edema. It is nonenhancing, as are the remaining smaller lesions. No lesions showing restricted diffusion.
Mild T2 weighted hyperintensity throughout the periventricular white matter, most in keeping with chronic small vessel ischemic change.
3 subcentimeter mature lacunar infarcts are present within the left head of caudate nucleus, anterior thalamus and anterior limb internal capsule, as seen on CT.
Impression:
Very numerous lesions throughout the brain with blooming artifact representing cavernomas. The appearance is consistent with familial multiple cavernous malformation syndrome.