Breast carcinoma with liver metastasis
Updates to Case Attributes
Due to the prevalence of ultrasonography and mammography, the diagnosis of breast carcinoma can be made at the earliest, thereby decreasing its mortality rate. However, there are cases where patients present in the later stage with lung, bone, brain, or liver metastases, which requiresrequire further evaluation. Metastatic disease to the liver from breast carcinoma is a known site, which can be hypovascular or hypervascular masses. Cross-sectional imaging, including CT, MRI, and PET-CT, is helpful in diagnosisdiagnosing and staging of the disease process.
-<p>Due to prevalence of ultrasonography and mammography, the diagnosis of breast carcinoma can be made at the earliest, thereby decreasing its mortality rate. However, there are cases where patients present in the later stage with lung, bone, brain, or liver metastases, which requires further evaluation. Metastatic disease to liver from breast carcinoma is a known site, which can be hypovascular or hypervascular masses. Cross-sectional imaging including CT, MRI, PET-CT is helpful in diagnosis and staging of the disease process.</p>- +<p>Due to the prevalence of ultrasonography and mammography, the diagnosis of breast carcinoma can be made at the earliest, thereby decreasing its mortality rate. However, there are cases where patients present in the later stage with lung, bone, brain, or liver metastases, which require further evaluation. Metastatic disease to the liver from breast carcinoma is a known site, which can be hypovascular or hypervascular masses. Cross-sectional imaging, including CT, MRI, and PET-CT, is helpful in diagnosing and staging the disease process.</p>
Systems changed:
- Breast
- Oncology
Updates to Link Attributes
Updates to Primarylink Attributes
Updates to Study Attributes
Heterogeneously enhancing large solid mass lesion involving entire right and caudate lobes of the liver with dystrophic calcifications and necrosis within, infiltrating the intrahepatic segment of inferior vena cava and right portal vein, extending into the left portal vein and main portal vein.
The gallbladder and right adrenal gland are not separately visualised.
Minimal ascites noted.
Enhancing lytic soft tissue lesion noted in left iliac bone.
Incidentally, visualised chest showed an enhancing lobulated soft tissue density lesion with central calcifications in the right breast.
A diagnosis of primary breast malignancy with liver and iliac bone metastases was suggested.
Updates to Study Attributes
8F-FDG Whole Body PET-CT
Metabolically active disease in the well-defined soft tissue density lesion in the outer quadrant of the right breast – site of the primary lesion.
Lung nodules showing faint metabolic activity – likely to be metastatic.
Low grade metabolic activity noted in large lesion involving the right lobe and the caudate lobe of the liver, showing calcifications within, with exophytic component and infiltration into the intrahepatic segment of inferior vena cava, right, left, and main portal vein – likely to be metastatic.
Hypermetabolic lytic lesion in left iliac bone – metastatic.
Updates to Freetext Attributes
Biopsy was performed from the breast and liver lesions under ultrasound guidance.
Biopsy from the upper outer quadrant of the right breast: Infiltrating ductal carcinoma – NOS; triple positive (ER/PR/HER-2 positive).
Biopsy from right lobe liver mass: metastatic carcinoma of breast origin.