Acoustic schwannoma

Case contributed by A.Prof Frank Gaillard

Presentation

Fall from horse. CT demonstrated abnormality.

Patient Data

Age: 16
Gender: Female
Modality: MRI

An extra-axial 25 x 40 mm lobulated mass in the left cerebellopontine angle corresponds to the lesion demonstrated on CT. It is T2 heterogeneously hyperintense with central suppression on FLAIR. T1 heterogeneous and hypointense to brain with peripheral vivid enhancement. The mass crosses the left internal auditory canal without extending into it and it does not appear to extend into the jugular foramen. It is continuous with the tentorial incisura superiorly without a clear dural tail. Central vascular flow voids on the T2 images are noted.

There is no diffusion restriction. MR spectroscopy voxel over the region demonstrates a reduced NAA peak with no evidence of significantly elevated lactate or lipids within the limitations of an erratic baseline. The lesion has increased peripheral perfusion.

The mass compresses and displaces the pons and left middle cerebral peduncle towards the right with distortion but not effacement of the fourth ventricle. The basilar artery lies close to its medial margin. High FLAIR signal in the middle cerebral peduncle is in keeping with vasogenic oedema. No hydrocephalus. The foramen magnum is crowded with bilateral tonsilar ectopia ( 4 mm below foramen magnum) .

Conclusion:

The appearance of the left cerebellopontine angle extra-axial mass most favours a vestibular schwannoma with a differential of cystic meningioma or metastasis considered less likely.

Case Discussion

MICROSCOPIC DESCRIPTION: The sections show a moderately cellular schwannoma. It mainly contains Antoni A areas with fascicles of spindle cells. There is focal palisading with Verocay body formation. Some microcystic change is noted. The tumour cells show no significant nuclear pleomorphism. Mitoses are inconspicuous. There is no evidence of necrosis. No evidence of malignancy is identified.

DIAGNOSIS: Schwannoma

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Case Information

rID: 28382
Case created: 24th Mar 2014
Last edited: 28th Aug 2015
Inclusion in quiz mode: Included

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