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Acquired hepatocerebral degeneration

Case contributed by Dr James Harvey


Unwitnessed falls. History of cirrhosis and portal hypertension secondary to chronic alcohol excess. Portal vein thrombosis.

Patient Data

Age: 65 years
Gender: Male
  • Symmetrical high T1 signal is seen within the globi pallidi, the ventral thalami, and the cerebral peduncles
  • Age advanced cerebral atrophy

Case Discussion

In this case, where there is supportive history of cirrhosis, acquired hepatocerebral degeneration is the most likely cause.

Manganese overload from other causes such as total parenteral nutrition could have the same appearance.

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Case information

rID: 86115
Published: 27th Jan 2021
Last edited: 28th Jan 2021
Inclusion in quiz mode: Included

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