Acute hyperammonemia

Case contributed by Ahmad Allababidi
Diagnosis almost certain

Presentation

Tetraparesis due to critical illness neuropathy. Acute liver failure. Hyperammonemia

Patient Data

Age: 50 years
Gender: Female
mri

Mild high FLAIR and high DWI signal (without low ADC signal) in the lateral putamen, external capsule, and claustrum and insula on both sides, as well as pons and mesencephalon slightly high signal.

Case Discussion

Symmetrical high FLAIR signal, affecting the lateral putamen, the external capsule, and claustrum on both sides as well as the pons and mesencephalon, primarily suspicious of acute hyperammonemic encephalopathy in acute liver failure, but without evidence of chronic hepatic leukoencephalopathy.

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