Acute interstitial pancreatitis with acute peripancreatic fluid collections

Case contributed by Dr Ahmed Nafea


Severe epigastric pain and vomiting

Patient Data

Age: 45
Gender: Female

Edematous pancreas with large acute peripancreatic fluid collections (APFCs). No CT evidence of pancreatic or peripancreatic necrosis.

Case Discussion

Pancreatitis is largely a clinical diagnosis made in patients with fever, nausea, and epigastric pain who have elevated serum amylase and lipase. The role of imaging is primarily to assess the severity and complications of the disease.


  • alcohol, gallstones, infection, hyperlipidemia, drugs, autoimmune disorders, and anatomic variability can all result in pancreatitis
  • imaging may show dilated loops of small bowel from nearby pancreatic inflammation or the “colon cut off sign
  • complications from pancreatitis include: necrosis, walled off necrosis, pseudoaneurysm formation, portosplenic vein thrombosis, shock, and disseminated intravascular coagulation.

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