Acute interstitial pneumonitis

Case contributed by Dr Hani Makky Al Salam


Progressive shortness of breath.

Patient Data

Age: 65 years
Gender: Female

Low lung volume with bi-basilar dependent atelectasis/consolidation. 


Bi-basilar and dependent ground glass opacities, interlobular septal thickening and mild traction broncheiactasis.


6 month follow up

There is progression of the bi-basilar traction broncheactasis and parenchymal architectural distortion of the lung bases.


One year from initial chest xray

Persistent low lung volume with bi-basilar atelectasis/scarring.


Another 6 month follow up

Persistent, essentially stable, bi-basilar traction broncheiactasis and architectural distortion. 

Case Discussion

This case demonstrates the typical findings of acute interstitial pneumonitis (AIP), considered a rapidly progressive interstitial disease of unknown etiology.

The disease suspicion confirmed by open lung biopsy; which demonstrates the combination of diffuse alveolar damage (DAD) along with some changes of cryptogenic organizing pneumonia (COP).

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Case information

rID: 45404
Published: 11th Oct 2018
Last edited: 17th Nov 2020
System: Chest
Inclusion in quiz mode: Included

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