Acute methanol intoxication
Progressive decrease level of consciousness, weakness and blurred vision.
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There is evidence of bilateral symmetrical low attenuation at both putamens with high attenuation putaminal foci consistent with hemorrhage. The post-contrast study demonstrates intense marginal contrast enhancement indicating blood-brain barrier damage. Appearances are consistent with acute putaminal necrosis due to methanol toxicity.
The patient clinical condition starts after proved oral ingestion of a large amount of methanol and the findings are attributed to putaminal toxic necrosis due methanol neurotoxicity.
Unlike ethanol, methanol is highly toxic and not proper for consumption. Methanol is usually present in industrial solvents, cleaning products and antifreeze liquids.
- CT and MR Imaging Findings in Methanol Intoxication M. Blancoa, R. Casadob, F. Vázqueza and J.M. Pumara.↵ Rubinstein D, Escott E, Kelly JP. Methanol intoxication with putaminal and white matter necrosis: MR and CT findings. AJNR Am J Neuroradiol 1995;16:1492–94 Abstract