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Acute necrotising encephalopathy

Case contributed by Huda B. Gharbia
Diagnosis almost certain

Presentation

Fever and upper respiratory tract symptoms for 4 days, developed status epilepticus and loss of consciousness.

Patient Data

Age: 1 year
Gender: Male

Bilateral almost symmetrical altered signal intensity of both thalami and caudate nuclei, appear peripheral hyperintense in T1W and hyperintense in T2W images and FLAIR sequences,

Also altered signal intensity of both cerebral hemispheres(more prominent in fronto-parietal lobes), involving cortical and subcortical region, with areas of restricted diffusion in DW/ADC sequences,

Little involvement of cerebellar hemispheres.

Also hyperintensity signal of brainstem(midbrain and pons), with focal area of blooming artifact in the pons.

Case Discussion

Symmetrical hyperintensity T2WI of cortical grey and white matter, thalami, brainstem and cerebellum and these findings preceded by fever and viral prodrome, suggestive acute necrotising encephalopathy.

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