Adamantinomatous craniopharyngioma

Case contributed by Mustafa Takesh
Diagnosis almost certain


Growth hormone deficiency and central hypothyroidism, for assessment.

Patient Data

Age: 8 years
Gender: Male

pre- and postoperative MRI


Selected MR images demonstrating a sellar/suprasellar cystic and solid mass lesion of irregular peripheral enhancement, extending within the pituitary stalk and reaching almost the hypothalamic region. Slight mass effect over the posterior aspect of optic chiasm.

The last images are postoperative and demonstrating subtotal resection of the tumor, with a thin residual tissue.

Case Discussion

8-year-old with growth hormone deficiency and central hypothyroidism presented to assess for congenital abnormality and pituitary lesion.

A sellar and suprasellar mass lesion with cystic and solid components was detected, for which the patient underwent surgery with subtotal resection. 

Histological examination revealed an adamantinomatous craniopharyngioma. No radiation therapy was carried out. The patient developed postoperative diabetes insipidus.

This case shows the importance of considering an adamantinomatous craniopharyngioma among the diagnosis options when we encounter a mixed sellar- and suprasellar cystic/solid lesion.

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