Adenocarcinoma colon with intussusception
Citation, DOI, disclosures and case data
At the time the case was submitted for publication Jini P Abraham had no recorded disclosures.View Jini P Abraham's current disclosures
Abdominal pain since 1 year; vomiting and increased frequency of passing stools since 2 months; fever since 1 day; CEA – 75.78 ng/ml
Loading Stack -
0 images remaining
Bowel wall thickening noted involving the hepatic flexure of colon, distal ascending colon and proximal transverse colon. Post contrast study shows no significant enhancement.
Intussusception of proximal ascending colon into the lesion noted.
Mild adjacent pericolic fat stranding noted.
Few mesenteric lymph nodes noted.
The above features were suggestive of a neoplastic growth with colo-colic intussusception.
Colonoscopy with biopsy was performed from the growth in proximal transverse colon.
Microscopy – sections show a predominantly exophytic tumor composed of pleomorphic columnar cells with hyperchromatic nuclei and moderate amount cytoplasm. These cells are arranged in glandular and villous configuration with pseudostratification. Irregular tubules are seen to infiltrate the muscularis mucosa. Surrounding stroma shows desmoplasia with chronic inflammatory infiltrate and pools of extravasated mucin.
Impression – Histological features suggestive of Adenocarcinoma in a background of villous adenoma.
Patient underwent right hemicolectomy.
Colonic intussusception are commonly associated with malignant tumors, including primary tumors (adenocarcinoma, lymphoma) and metastases. Colonic intussusception usually presents in a subacute manner with prolonged abdominal pain and constipation.
- 1. Inada R. Intussusception due to rectal adenocarcinoma in a young adult: A case report. World Journal of Gastroenterology. 2014;20(35):12678.
- 2. Kim Y, Blake M, Harisinghani M, Archer-Arroyo K, Hahn P, Pitman M et al. Adult Intestinal Intussusception: CT Appearances and Identification of a Causative Lead Point. RadioGraphics. 2006;26(3):733-744.
- 3. Gollub M. Colonic Intussusception: Clinical and Radiographic Features. American Journal of Roentgenology. 2011;196(5):W580-W585.