Adrenal collision tumor (ACT)

Case contributed by Dr Domenico Nicoletti


Follow up lung cancer.

Patient Data

Age: 70 years
Gender: Female

Right adrenal gland contains a 3.5 cm round mass, composed of two different tissues. The predominant part has basal densitometric values and typical wash out for adenoma. There is also a nodule with higher baseline densitometric values and less washout compatible with secondary metastatic lesions.

Annotated image

Within the right adrenal adenoma, there is vascularized solid tissue attributable to metastases from the pulmonary neoplasm.

Case Discussion

Adrenal collision tumors (ACT) are the coexistence of two adjacent histologically distinct neoplasms, without histological mixing.

ACTs include adenoma with myelolipoma, adenoma with metastasis, hemangioma with adenoma and adrenocortical carcinoma with myelolipoma.

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