Adrenoleukodystrophy

Case contributed by Dr Salman Albakheet

Presentation

History of seizures and visual disturbance.

Patient Data

Age: Child
Gender: Male

MRI Brain

Modality: MRI

There is evidence of bilateral symmetrical confluent low Tl signal and high T2 signal involving peritrigonal white matter, optic radiation as well as splenium and extending to involve the corticospinal tracts. The subcortical U-fiber white matter is spared.  The "leading edge" also demonstrates enhancement after Gadolinium injection.  Additionally there is bilateral symmetrical auditory pathways involvement at the level of brain stem (pons) with enhancement after contrast injection. 

Case Discussion

These MRI features are typical for X-linked adrenoleukodystrophy and the diagnosis of this case was confirmed.

PlayAdd to Share

Case Information

rID: 33377
Case created: 9th Jan 2015
Last edited: 7th Aug 2016
Inclusion in quiz mode: Included

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.