Advanced osteonecrosis (sickle cell disease)

Case contributed by Dr Fakhry Mahmoud Ebouda


Patient suffering from sickle cell disease.

Patient Data

Age: 22 years.
Gender: Male

Right femoral and left humeral head deformities are seen. Irregularities, sclerosis mixed with lucencies are seen. An associated femoral neck deformity is seen. Radiographic findings are matching with avascular necrosis of the corresponding femoral as well as humeral heads. Crescent sign of avascular necrosis is seen on conventional radiographs, and seen as a linear area of subchondral lucency depicted usually within the anterolateral aspect of the proximal femoral head. 


Case Discussion

Avascular necrosis is a process that results from interruption of blood supply to the bone. Etiopathogenesis is incompletely understood. Sickle cell anemia is a common cause of that compromise circulation to either femoral or humeral heads. Osteonecrosis of the humeral head (ONHH) (also known as Hass disease).

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Case information

rID: 42880
Published: 12th Feb 2016
Last edited: 14th Aug 2019
Inclusion in quiz mode: Excluded

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