Allergic bronchopulmonary aspergillosis
- Integral Diagnostics, Shareholder (ongoing)
- Micro-X Ltd, Shareholder (ongoing)
Updates to Case Attributes
Allergic bronchopulmonary aspergillosis (ABPA) is a fungal infection of the lung due to a hypersensitivity reaction to antigens of Aspergillus fumigatus after colonisation into the airways.
Predominantly it affects uncontrolled asthmatics, cystic fibrosis patients, and immunocompromised patients
Diagnosis. The diagnosis centres around classic clinical manifestations, radiographic findings, and immunological findings.
In this case, the clinical history consisting in a long standing severe asthma with difficult terapeuticaltherapeutic control, the laboratory test results (Elevated(elevated Inmunoglobulina E: 6968,0 UI/mL , peripheral eosinophilia : 0,61 x 10^3/µL (0,00 - 0,50) ) as well as the characteristic radiological findings: central bronchiectasis predominantly in the upper lobes with mucoid impactationimpaction resulting in bronchocoelebronchocele formation (giving the characteristic 'finger in glove ' sign) associated with recurrent episodes of pulmonary superinfections support the diagnosis of allergic bronchopulmonary aspergillosisABPA.
-<p></p><p>Allergic bronchopulmonary aspergillosis (ABPA) is a fungal infection of the lung due to a hypersensitivity reaction to antigens of <em>Aspergillus fumigatus</em> after colonisation into the airways. </p><p>Predominantly it affects uncontrolled asthmatics, cystic fibrosis patients, and immunocompromised patients</p><p>Diagnosis centres around classic clinical manifestations, radiographic findings, and immunological findings</p><p>In this case, the clinical history consisting in a long standing severe asthma with difficult terapeutical control, the laboratory test results (Elevated Inmunoglobulina E: 6968,0 UI/mL , peripheral eosinophilia : 0,61 x 10^3/µL (0,00 - 0,50) ) as well as the characteristic radiological findings: central bronchiectasis predominantly in the upper lobes with mucoid impactation resulting in bronchocoele formation (giving the characteristic 'finger in glove ' sign) associated with recurrent episodes of pulmonary superinfections support the diagnosis of allergic bronchopulmonary aspergillosis. </p><p></p><p></p><p></p>- +<p><a href="/articles/allergic-bronchopulmonary-aspergillosis" title="Allergic bronchopulmonary aspergillosis (ABPA)">Allergic bronchopulmonary aspergillosis (ABPA)</a> is a fungal infection of the lung due to a hypersensitivity reaction to antigens of <em>Aspergillus fumigatus</em> after colonisation into the airways. Predominantly it affects uncontrolled asthmatics, cystic fibrosis patients, and immunocompromised patients. The diagnosis centres around classic clinical manifestations, radiographic findings, and immunological findings.</p><p>In this case, the clinical history consisting in a long standing severe asthma with difficult therapeutic control, the laboratory test results (elevated Inmunoglobulina E: 6968,0 UI/mL , peripheral eosinophilia : 0,61 x 10^3/µL (0,00 - 0,50) ) as well as the characteristic radiological findings: central bronchiectasis predominantly in the upper lobes with mucoid impaction resulting in bronchocele formation (giving the characteristic 'finger in glove ' sign) associated with recurrent episodes of pulmonary superinfections support the diagnosis of ABPA.</p><p></p><p></p><p></p>
Updates to Study Attributes
Diffuse airway disease with varicose-type bronchiectasis involvement that predominates in the upper lobes, internal segment of the middle lobe, apical segments of the left lower lobe. There is some respect of the lingula and the right lower lobe.Occupation
Opacification of bronchiectasis of the apical and lateral segment of the left lower lobe and partially of those located in the apical segment of the right lower lobe by increased density secretions in a ‘finger in glove pattern’.
Extensive centrilobular micronodularity and 'tree in bud' pattern .
Ground glass opacities are also observed in the internal and anterior aspect of the right base of keeping with acute small airway bronchiolitic process.No abscess areas or cavitated consolidations were identifiedconsolidation.
No pericardial or pleural effusion.No lymphadenopathy.
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