Alpha-1-antitrypsin deficiency

Case contributed by Bruno Di Muzio
Diagnosis almost certain

Patient Data

Age: 65 years
Gender: Female

Chest radiographs

x-ray

Patchy hyper lucency throughout both lungs suggesting emphysema. No air-space opacities or pleural effusion. No pneumothorax or subphrenic free gas. The cardiomediastinal contours are within the normal limits. 

CT Chest

ct

Areas of panlobular emphysema scattered throughout both lungs without a clear lobar predilection. 

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