Alpha 1 antitrypsin deficiency
Worsening dyspnea on exertion. No infective symptoms.
Loading Stack -
0 images remaining
Increased lung volumes with symmetric hyperlucency in the lower zones. Thick verticle band of plate atelectasis in the left lower zone. Pleural spaces are clear. Cardiomediastinal contours are normal.
Given the findings of basal emphysema, alpha 1 antitrypsin deficiency was suspected and LFTs were subsequently derranged. The patient had confirmation of the disease with low serum alpha 1 antitrypsin (AAT) levels and genetic testing revealed SZ genotype.