Alpha 1 antitrypsin deficiency

Case contributed by Dr Paul Leong

Patient Data

Age: 56
Gender: Female

The lungs are hyperinflated with relative hyperlucency of the lower zones.


The lungs are hyperinflated.

There is hyperlucency of the lower zones, relative to the upper zones. 

This distribution is suggestive of alpha 1 antitrypsin deficiency related lung disease.

Case Discussion

The diagnosis of alpha 1 antityrpsin deficiency was confirmed in this patient after blood tests revealed low serum alpha-1 antitrypsin levels.

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Case information

rID: 26537
Published: 27th Dec 2013
Last edited: 14th Aug 2019
System: Chest
Tag: crop
Inclusion in quiz mode: Included

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