Alpha-1-antitrypsin deficiency

Case contributed by Dr Abdallah Alqudah



Patient Data

Age: 50 years
Gender: Male

Panlobular emphysematous changes diffusely replacing the lower lobes of both lungs with very thin internal septa but no residual lung tissue seen. Similar, yet, less severe changes are seen in the medial lobe of the right lung where interspersed lung tissue is seen.

Centrilobular and paraseptal emphysematous changes involving the upper lobes of both lungs.

Subsegmental area of consolidation with air bronchograms seen in the inferior segment of the lingula.

Case Discussion

Severe lower lobe predominant panlobular emphysematous changes with no residual lung tissue seen. In a middle aged patient, these changes may be secondary to alpha-1-antitrypsin deficiency

PlayAdd to Share

Case information

rID: 50561
Published: 11th Jan 2017
Last edited: 29th Nov 2019
System: Chest
Inclusion in quiz mode: Included