Cyber Monday 50% Off! Get our cervical spine x-ray interpretation course for just $9 LEARN MORE

Alzheimer disease

Case contributed by Dr Bruno Di Muzio


Patient with cognitive impairment.

Patient Data

Age: 55 years
Gender: Female

Brain CT

CT scan shows enlargement of cerebral sulci and loss of gyral volume associated with mild compensatory dilation of the ventricular system. This is perhaps most marked in the parietal regions. These are nonspecific findings that are sometimes found in the asymptomatic population in this age group.

Nuclear medicine

Positron emission tomography (PET)

PET-CT uses radiolabeled glucose analog FDG to measure glucose metabolism, which indicates levels of neuro-synaptic activity. On these FDG PET images, it is seen decreased metabolism activity on the bilateral parietotemporal cortex.

Nuclear medicine

PET-CT (fusion of images)

FDG PET-CT images show decreased metabolic activity in the bilateral parietotemporal cortex.

Case Discussion

This patient not only had cognition and memory impairment over the last 6 months but also had a family history of Alzheimer disease.

The severe hypometabolism noted in the temporal and parietal regions bilaterally is consistent with the pattern of Alzheimer disease.

PlayAdd to Share

Case information

rID: 22715
Published: 18th Apr 2013
Last edited: 4th Jul 2020
Inclusion in quiz mode: Included

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.