Alzheimer's disease (PET CT)

Case contributed by Dr Bruno Di Muzio

Presentation

Patient with cognitive impairment.

Patient Data

Age: 55 years
Gender: Female
CT

Brain CT

CT scan shows enlargement of cerebral sulci and loss of gyral volume associated with mild compensatory dilation of the ventricular system. This is perhaps most marked in the parietal regions. These are nonspecific findings that are sometimes found in the asymptomatic population in this age group.

Nuclear medicine

Positron emission tomography (PET)

PET-CT uses radiolabeled glucose analogue FDG to measure glucose metabolism, which indicates levels of neuro-synaptic activity. On these FDG PET images, it is seen decreased metabolism activity on the bilateral parietotemporal cortex.

Nuclear medicine

PET-CT (fusion of images)

FDG PET-CT images show decreased metabolism activity on bilateral parietotemporal cortex.

Case Discussion

This patient not only had cognition and memory impairment over the last 6 months but also had a family history of Alzheimer's disease.

The severe hypometabolism noted in the temporal and parietal regions bilaterally is consistent with the pattern of Alzheimer's Disease.

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Case information

rID: 22715
Case created: 18th Apr 2013
Last edited: 25th Oct 2017
Inclusion in quiz mode: Included

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