Amiodarone deposition in the liver

Case contributed by Ammar Ashraf

Diagnosis certain

Citation, DOI, disclosures and case data

Citation:

Ashraf A, Amiodarone deposition in the liver. Case study, Radiopaedia.org (Accessed on 25 Apr 2024) https://doi.org/10.53347/rID-77587

DOI:

https://doi.org/10.53347/rID-77587

Permalink:

https://radiopaedia.org/cases/77587?iframe=true

rID:

77587

Disclosures:

At the time the case was submitted for publication Ammar Ashraf had no recorded disclosures.

Case published:

22 May 2020

Revisions:

2 times, by 1 contributor - see full revision history and disclosures

Systems:

Hepatobiliary

Institution:

King Abdulaziz Hospital Al Ahsa (MNGHA)

Quiz mode:

Included

Complain of bilateral chest pain & backache for 1 week after a history of fall down in the bathroom.

Age: 80 years

Gender: Female

From the case: Amiodarone deposition in the liver

Multiple recent bilateral rib fractures (non-displaced fractures of the right posterolateral 6th, 7th, 8th, & 9th ribs and fractured left 9th & 11th ribs close to the costovertebral junction) and old/healed fracture of the left 2nd rib anteriorly.
Fractured right transverse processes of the 6th, 7th, 8th, & 9th vertebrae.
Diffuse osteopenia, dorsal spondylosis, and a superior endplate compression fracture of the 11th dorsal vertebra without any retropulsion.
Mild cardiomegaly. Evidence of previous sternotomy/cardiac surgery/valve replacement is noted.
Mild bilateral pleural effusions with changes of collapse/atelectasis in the underlying lungs.
Small hyperdense focus measuring 7 x 9 mm (average density=950 HU) at the gastroesophageal junction (patient took some tablets just before the CT scan).
Incidental finding of increased hepatic attenuation (average density=84 HU).

Detailed history: Hypertension, rheumatic heart disease, atrial fibrillation & ventricular tachycardia.
Multiple cardiac surgeries (CABG, mitral valve replacement, tricuspid valve repair, and PFO closure).
Drugs (atenolol, amiodarone, digoxin, and warfarin).
Increased hepatic attenuation, was an incidental finding, in this case, which was likely one of the complications/side effects related to the amiodarone therapy (Amiodarone deposition in the liver).