Amiodarone hepatotoxicity

Case contributed by Dr Chris O'Donnell

Presentation

Severe dilated cardiomyopathy on amiodorone for the last 3 years. Now abdominal pain and nausea.

Patient Data

Age: 70
Gender: Male
CT

Non-contrast CT as patient has chronic renal impairment

Liver has become hyperdense ie mean HU = 74 (note blood vessels are low density in relation to the parenchyma).  Previously in 2009 mean HU = 39.  The patient has been on amiodorone for the last 3 years.  In that time the patient has developed CT signs of portal hypertension ie splenomegaly and enlargement of the portal vein.

CT

CT scan in 2009

The previous study showing the normal hepatic attenuation in HU

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Case information

rID: 19990
Case created: 27th Oct 2012
Last edited: 8th Feb 2016
Inclusion in quiz mode: Included

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