Amnestic syndrome secondary to hypoxic brain injury


35 year old gentleman referred for assessment of rapid forgetting following heroin overdose. Unremarkable mental state and neurological examinations.

Patient Data

Age: 35
Gender: Male

Bedside cognitive testing


Attention: 12/20

Visuoconstructional: 18/20

Memory: 7/20

Executive: 17/20

Language: 18/20

Total: 70/100

Prominent bilateral hippocampal T2 hyperintensity with restricted diffusion on DWI

Case Discussion

Unresolving amnestic syndrome associated with bilateral hippocampal lesions on acute imaging. The likely etiology is hypoxic-ischemic brain damage sustained in the course of heroin overdose.

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