Amyotrophic lateral sclerosis

Case contributed by Dr Heba Abdelmonem


Gradual onset progressive quadriparesis with hypereflexia, hypertonia and tongue fasciculation.

Patient Data

Age: 50 years
Gender: Female

Abnormally increased T2 / FLAIR signals in the posterior limb of both internal capsules, extending superiorly to the subcortical white matter of motor cortex and inferiorly along the corticospinal tracts.

Case Discussion

MRI findings and clinical data is highly characteristic for Amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive degeneration of upper motor neurons (UMN) and lower motor neurons (LMN).

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Case information

rID: 88966
Published: 25th Apr 2021
Last edited: 29th Apr 2021
Inclusion in quiz mode: Included
Institution: Zagazig University Hospital

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