Amyotrophic lateral sclerosis
Gradual onset progressive quadriparesis with hypereflexia, hypertonia and tongue fasciculation.
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Abnormally increased T2 / FLAIR signals in the posterior limb of both internal capsules, extending superiorly to the subcortical white matter of motor cortex and inferiorly along the corticospinal tracts.
MRI findings and clinical data is highly characteristic for Amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive degeneration of upper motor neurons (UMN) and lower motor neurons (LMN).