Angioinvasive aspergellosis

Case contributed by Ahmed Abdrabou
Diagnosis almost certain


Known patient with bladder cancer received chemotherapy and became immunocompromised. He had dyspnea, cough, chest pain and recurrent fever of 2 months duration. The study was done for search of metastasis.

Patient Data

Age: 55 years
Gender: Male

Few small nodules are noted at the left lower lung lobe with typical halo sign of ground glass attenuation around them. Other findings include small areas of ground glass attenuation scattered at both lungs and apical emphysematous changes. Few mediastinal lymphadenopathies are also noted. No pleural effusion. 

Annotated image

The black circle refers to a nodule with ground glass halo around. 

Case Discussion

The left lower lobe nodules are not typical for metastasis from bladder cancer. They've typical ground glass halo around which is suggestive for angioinvasive aspergellosis. The patient received fungal treatment and recovered clinically. 

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